Pooled Human Immunoglobulin Preparations as Immunomodulating Drugs
نویسندگان
چکیده
منابع مشابه
Immunomodulating Drugs
Immunopharmacology is the study of the use of pharmacological agents as modulators of immune responses. The principal applications are in the use of immunosuppressive agents (i.e., compounds that suppress undesirable immune responses) and immunostimulating agents (i.e., drugs, microorganisms, or biological products that enhance or augment immune responses). Three major indications for immunothe...
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Background: In this study we have prepared the IgA solution from normal human plasma using plasma fractionation and ion exchange chromatography. Materials and Methods: Using fractionation of plasma with cold ethanol (starting with 8% ethanol), fraction III was prepared as a suitable source for IgA preparation. Then it was treated with caprylic acid for separation of impurities. For enrichm...
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OBJECTIVE To examine the use of intravenous immunoglobulin (i.v.i.g.) in chronic pain. DESIGN A prospective multiple-dose, open-label cohort study in 130 consecutive patients who suffered from 12 chronic pain syndromes. The largest symptom groups were (number of patients): Fibromyalgia (48); Spinal pain (20); Complex regional pain syndrome (CRPS, 11); Peripheral neuropathic pain (12); and Aty...
متن کاملimmunoglobulin a preparation from human pooled plasma using plasma fractionation and ion exchange chromatography
background: in this study we have prepared the iga solution from normal human plasma using plasma fractionation and ion exchange chromatography. materials and methods: using fractionation of plasma with cold ethanol (starting with 8% ethanol), fraction iii was prepared as a suitable source for iga preparation. then it was treated with caprylic acid for separation of impurities. for enrichment o...
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Intravenous immunoglobulin (IVIg) therapy is increasingly used for its immunomodulating properties in a wide range of pathological conditions including autoimmune diseases, systemic inflammatory diseases and allotransplantation. Intravenous immunoglobulins are obtained from a pool of several thousand healthy blood donors. They are composed of intact IgG with a distribution of subclasses corresp...
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ژورنال
عنوان ژورنال: Molecular Biology
سال: 2019
ISSN: 0026-8933,1608-3245
DOI: 10.1134/s0026893319050145